Distinguished Investigators Join the NIAAA Division of Intramural Clinical and Biological Research

In 2019, two distinguished investigators joined the National Institute on Alcohol Abuse and Alcoholism (NIAAA) Division of Intramural Clinical and Biological Research (DICBR).

An image of Dr. Michelle Antoine smiling at the cameraMichelle Antoine, Ph.D., is a National Institutes of Health (NIH) Earl Stadtman Tenure-Track Investigator in the DICBR Intramural Research Program. The Stadtman program recruits highly talented and diverse early-career scientists. Dr. Antoine’s research deciphers genetic and environmental factors that impair neurocircuit activity, leading to neurodevelopmental disorders. Her recent work on neuron signal activity led to important new insights into autism spectrum disorder. At NIAAA, Dr. Antoine is applying her basic research experience in neurocircuit function to neurodevelopmental comorbidities commonly seen in fetal alcohol spectrum disorders. Her research findings have been published in prominent scientific journals and highlighted in both the U.S. and international media. Dr. Antoine earned her doctorate from the Albert Einstein College of Medicine in New York and completed her postdoctoral training as a Miller Research Fellow in the Helen Wills Neuroscience Institute at the University of California, Berkeley. At NIAAA, she serves as Acting Chief of the Section on Neural Circuits in the Office of the Scientific Director.

An image of Dr. Paule Joseph smiling at the cameraPaule Valery Joseph, Ph.D., was named one of NIH’s 2019 Lasker Clinical Research Scholars. Dr. Joseph received a joint appointment with NIAAA and the National Institute of Nursing Research, where she leads the Sensory Science and Metabolism Unit. The Lasker Clinical Research Scholars program allows early-stage clinician-scientists to conduct independent clinical and translational research at NIH. Dr. Joseph is collaborating with several DICBR investigators; these include Dr. Nora Volkow (NIAAA Laboratory of Neuroimaging) and Dr. Lorenzo Leggio (Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, a joint NIAAA-National Institute on Drug Abuse laboratory). A focus of Dr. Joseph’s research at NIAAA is to explore, at the neurobiological level, how senses such as smell and taste are involved in cues that trigger craving for alcohol, a diagnostic feature of alcohol use disorder. Dr. Joseph received her bachelor of science in nursing from the College of New Rochelle, New York, and her doctorate in nursing with a focus on genomics from the University of Pennsylvania.